Sinopharm COVID-19 vaccine: All you need to know

  • Dubai: The UAE, along with Bahrain, were two of the first Arab countries to approve the Sinopharm shot — and were the first countries to grant full approval to use a COVID-19 vaccine. Other countries followed suit. Here’s a closer look into the Sinopharm vaccine and how the UAE leads the world in the fight against the pandemic.To get more news about sinopharm vaccine, you can visit shine news official website.

    Sinopharm’s China National Biotec Group (CNBG). Sinopharm is a Chinese state-owned biotech company based in Beijing.Reuters reported in September that Phase III trials for the Sinopharm shot had been conducted in 10 countries worldwide. The vaccine has been granted authorisation in China, and several other countries, including the UAE.

    A vaccine trial is best done in places where a pathogen (like SARS-CoV-2) is still most active. In China, the case numbers had dropped significantly in the third quarter of 2020, due to the strict lockdowns. Doing a trial there would have made it difficult to obtain any meaningful data at all.

    Once inside the body, given through intra-muscular injection, some of the inactivated viruses are swallowed up by a type of immune cell called an "antigen-presenting cell". The antibodies also attach to viral proteins, such as the so-called spike proteins that populate the viral surface.

    The journal Cell explains: to create Sinopharm’s BBIBP-CorV shot, the researchers obtained three variants of the coronavirus from patients in Chinese hospitals. They picked one of the variants because it was able to multiply quickly in monkey kidney cells grown in bioreactor tanks.

    It’s a tried-and-tested platform. Inactivated viruses have been used for over 100 years. Polio vaccine inventor Jonas Salk used them to create his polio vaccine in the 1950s. It’s the same method used to prepare vaccines against other diseases including rabies and hepatitis A. Coronaviruses in BBIBP-CorV are literally killed (inactivated) through a chemical process, so they can be injected into your arm without causing COVID-19.

    Yes, they are literally killed. But first, before they’re killed, lab workers produce huge stocks of the coronaviruses in high bio-safety labs. Once the desired quantities are produced, they are doused with a chemical called “beta-propiolactone”.

    The compound disables the coronaviruses by bonding to their genes. Therefore, inactivated coronaviruses could no longer replicate. But their proteins, including spike, are still whole — as in intact — which is useful in prompting response from our body’s immune response via antibodies, T cells and B cells against infectious diseases.

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